Directions: From the Intersection of Hwy. 17 and Hwy. 521 in Georgetown, take Hwy 17 south and travel 1.9 miles to South Island Road. Take a slight left onto South Island Road and travel 7.5 miles to Estherville Road. Take a right onto Estherville Road and travel 2.8 miles to Annandale Road on the left. Annandale Road is unpaved and a PRIVATE ROAD. GATE ACCESS IS REQUIRED.
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Annandale Plantation of Georgetown County, SC
Archives & Records of the Plantations of South Carolina
by Mrs. Johnie Rivers
http://lowcountryplantations.org/index.php?filename=plantation.php&id=1196
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Annandale Plantation, originally named Millbrook, the site of the first tide-operated rice mill constructed in the state (ca. 1792), is one of South Carolina's finest remaining examples of the rice-plantation era. During the 1850s, Annandale was among the most prosperous of the rice plantations, working approximately 230 slaves and producing 900,000 pounds of rice. Andrew Johnston's father bequeathed the property to him, and he built the present plantation house in 1833. At that time he renamed the property Annandale after the birthplace of his ancestors in Annandale, Scotland. This two story Greek Revival structure, c.1833, is an excellent example of its style and period. Situated in a grove of live oaks and landscaped gardens, Annandale includes two existing outbuildings: a slave cabin which has been converted into a recreation building and the plantation-doctor's house, now a residence. Listed in the National Register October 25, 1973.

South Carolina Department of Archives and History
National Register Properties in South Carolina
Annandale Plantation, Georgetown County
(off S.C. Sec. Rd. 30, North Santee vicinity)
http://www.nationalregister.sc.gov/georgetown/S10817722007/index.htm
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National Register of Historic Places Inventory - Nomination Form for Annandale Plantation
Between S.C. 30 and S.C. 18 and Estherville Creek Canal (Intra-Coastal Waterway) and North Santee River about 14 miles South of Georgetown
http://www.nationalregister.sc.gov/georgetown/S10817722007/S10817722007.pdf